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De los Santos retired one batter and allowed one hit and one walk in the sixth inning in a 3-2 loss to the visiting Los Angeles Angels on Wednesday night.
To replace him in the bullpen, the team signed left-hander Jayvien Sandridge to a major league contract and called him up from Triple-A Scranton/Wilkes-Barre.
Sandridge, 26, is in his seventh season in the minors and has yet to make his MLB debut. He is 1-1 with a 3.00 ERA and two saves in 10 games (no starts) at three levels this season.
To make room on the 40-man roster for Sandridge, the Yankees transferred infielder/outfielder Oswaldo Cabrera (fractured left ankle) to the 60-day injured list.
