The 23-year-old Misiorowski stayed in the game, pitching three more innings before coming out after 80 pitches.
Misiorowski is 4-1 with 47 strikeouts in 33⅓ innings this season.
In a related move, the Brewers recalled right-hander Logan Henderson from Triple-A Nashville, and he is expected to start against the Nationals on Sunday.
The Associated Press contributed to this report.